Synthesis and secretion of steroid hormones

Falciform ligament – attaches the anterior surface of the liver to the anterior abdominal wall. The free edge of this ligament contains the ligamentum teres, a remnant of the umbilical vein.

  • Coronary ligaments (anterior and posterior folds)teac  – attach the superior surface of the liver to the diaphragm .
  • Triangular ligaments (left and right) – attach the superior surface of the liver to the diaphragm.
  • Lesser omentum – consists of the hepatoduodenal ligament (extends from the duodenum to the liver), and the hepatogastric ligament (extends from the stomach to the liver).
In addition to these supporting ligaments, the posterior surface of the liver is secured to the inferior vena cava by hepatic veins and fibrous tissue.

Cholic acid , 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, the most abundant bile acid in humans and many other species, was discovered before chenodeoxycholic acid. It is a tri-hydroxy-bile acid with 3 hydroxyl groups (3α, 7α and 12α). In its synthesis in the liver, 12α hydroxylation is performed by the additional action of CYP8B1 . As this had already been described, the discovery of chenodeoxcholic acid (with 2 hydroxyl groups) made this new bile acid a "deoxycholic acid" in that it had one fewer hydroxyl group than cholic acid. [2] [3]

Synthesis and secretion of steroid hormones

synthesis and secretion of steroid hormones

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