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Teva developed a long-acting 40 mg formulation, marketed since 2015, which reduced required injections to three per week. [23] Sandoz is also developing a generic long-acting version, Momenta Pharmaceuticals M356, which is yet to be approved by the FDA and has been subject to a technical FDA warning letter. [24] [25] In October 2017, the FDA approved a generic version, which is manufactured in India by NATCO Pharma , and imported and sold by Dutch firm Mylan . [26] [27] In parallel with the development and approval processes, the generic competitors have disputed Teva's newer patents, any of which if upheld, would prevent marketing of long-acting generics. [28]

Injectable steroids are injected into muscle tissue, not into the veins. They are slowly released from the muscles into the rest of the body, and may be detectable for months after last use. Injectable steroids can be oil-based or water-based. Injectable anabolic steroids which are oil-based have longer half-life than water-based steroids. Both steroid types have much longer half-lives than oral anabolic steroids. And this is proving to be a drawback for injectables as they have high probability of being detected in drug screening since their clearance times tend to be longer than orals. Athletes resolve this problem by using injectable testosterone early in the cycle then switch to orals when approaching the end of the cycle and drug testing is imminent.




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