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Along with the incredible potency of methyltrienolone comes some very strong side effects. Methyltrienolone is very androgenic and is likely to cause hair loss and severe acne in those who are prone to these effects. There is some risk for gynecomastia due to the progestational effects of methyltrienolone. The biggest concern with Methyltrienolone is probably its liver toxicity. Even at very low doses, methyltrienolone can cause significant liver stress in a very short period of time. This may possibly be the most liver toxic steroid in existence, and it is definitely not recommended to use methyltrienolone for any longer than 4 weeks at a time.